Author’s response to reviews Title: Is there continued evidence for an association between abacavir usage and myocardial infarction risk in individuals with human immunodeficiency virus (HIV)?: a cohort collaboration Authors:
نویسندگان
چکیده
Authors: Caroline Sabin ([email protected]) Peter Reiss ([email protected]) Lene Ryom ([email protected]) Andrew Phillips ([email protected]) Rainer Weber ([email protected]) Matthew Law ([email protected]) Eric Fontas ([email protected]) Amanda Mocroft ([email protected]) Stephane de Wit ([email protected]) Colette Smith ([email protected]) Francois Dabis ([email protected]) Antonella d'Arminio Monforte ([email protected]) Wafaa El-Sadr ([email protected]) Jens Lundgren ([email protected])
منابع مشابه
No risk of myocardial infarction associated with initial antiretroviral treatment containing abacavir: short and long-term results from ACTG A5001/ALLRT.
BACKGROUND Observational and retrospective clinical trial cohorts have reported conflicting results for the association of abacavir use with risk of myocardial infarction (MI), possibly related to issues that may bias estimation of treatment effects, such as time-varying confounders, informative dropout, and cohort loss due to competing events. METHODS We analyzed data from 5056 individuals i...
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متن کاملIs there continued evidence for an association between abacavir usage and myocardial infarction risk in individuals with HIV? A cohort collaboration.
BACKGROUND In March 2008, the D:A:D study published results demonstrating an increased risk of myocardial infarction (MI) for patients on abacavir (ABC). We describe changes to the use of ABC since this date, and investigate changes to the association between ABC and MI with subsequent follow-up. METHODS A total of 49,717 D:A:D participants were followed from study entry until the first of an...
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